Acquired functional capsid structures in metazoan totivirus-like dsRNA virus

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00534058" target="_blank" >RIV/68378271:_____/20:00534058 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.str.2020.04.016" target="_blank" >https://doi.org/10.1016/j.str.2020.04.016</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.str.2020.04.016" target="_blank" >10.1016/j.str.2020.04.016</a>

Result language
angličtina
Original language name
Acquired functional capsid structures in metazoan totivirus-like dsRNA virus
Original language description
Non-enveloped icosahedral double-stranded RNA (dsRNA) viruses possess multifunctional capsids required for their proliferation. Whereas protozoan/fungal dsRNA viruses have a relatively simple capsid structure, which suffices for the intracellular phase in their life cycle, metazoan dsRNA viruses have acquired additional structural features as an adaptation for extracellular cell-to-cell transmission in multicellular hosts. Here, we present the first atomic model of a metazoan dsRNA totivirus-like virus and the structure reveals three unique structural traits: a C-terminal interlocking arm, surface projecting loops, and an obstruction at the pore on the 5-fold symmetry axis.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10610 - Biophysics

Project
<a href="/en/project/EF15_003%2F0000447" target="_blank" >EF15_003/0000447: Structural dynamics of biomolecular systems</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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