Functionalizable antifouling coatings as tunable platforms for the stress-driven manipulation of living cell machinery
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00538757" target="_blank" >RIV/68378271:_____/20:00538757 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/20:00116149
Result on the web
<a href="http://hdl.handle.net/11104/0316495" target="_blank" >http://hdl.handle.net/11104/0316495</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/biom10081146" target="_blank" >10.3390/biom10081146</a>
Alternative languages
Result language
angličtina
Original language name
Functionalizable antifouling coatings as tunable platforms for the stress-driven manipulation of living cell machinery
Original language description
Cells are continuously sensing their microenvironment and subsequently respond to di erent physicochemical cues by the activation or inhibition of di erent signaling pathways. To study a very complex cellular response, it is necessary to diminish background environmental influences and highlight the particular event. However, surface-driven nonspecific interactions of the abundant biomolecules from the environment influence the targeted cell response significantly. Yes-associated protein (YAP) translocation may serve as a marker of human hepatocellular carcinoma (Huh7) cell responses to the extracellular matrix and surface-mediated stresses. Here, we propose a platform of tunable functionable antifouling poly(carboxybetain) (pCB)-based brushes to achieve a molecularly clean background for studying arginine, glycine, and aspartic acid (RGD)-induced YAP-connected mechanotransduction.n
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10610 - Biophysics
Result continuities
Project
<a href="/en/project/EF16_019%2F0000760" target="_blank" >EF16_019/0000760: Solid State Physics for 21st century</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomolecules
ISSN
2218-273X
e-ISSN
—
Volume of the periodical
10
Issue of the periodical within the volume
8
Country of publishing house
CH - SWITZERLAND
Number of pages
14
Pages from-to
1-14
UT code for WoS article
000577776900001
EID of the result in the Scopus database
2-s2.0-85089300955