Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00543374" target="_blank" >RIV/68378271:_____/20:00543374 - isvavai.cz</a>
Result on the web
<a href="http://hdl.handle.net/11104/0320589" target="_blank" >http://hdl.handle.net/11104/0320589</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41597-020-00729-2" target="_blank" >10.1038/s41597-020-00729-2</a>
Alternative languages
Result language
angličtina
Original language name
Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs
Original language description
Structural studies of challenging targets such as G protein-coupled receptors (GPCRs) have accelerated during the last several years due to the development of new approaches, including small-wedge and serial crystallography. Here, we describe the deposition of seven datasets consisting of X-ray diffraction images acquired from lipidic cubic phase (LCP) grown microcrystals of two human GPCRs, Cysteinyl leukotriene receptors 1 and 2 (CysLT(1)R and CysLT(2)R), in complex with various antagonists. Five datasets were collected using small-wedge synchrotron crystallography (SWSX) at the European Synchrotron Radiation Facility with multiple crystals under cryo-conditions. Two datasets were collected using X-ray free electron laser (XFEL) serial femtosecond crystallography (SFX) at the Linac Coherent Light Source, with microcrystals delivered at room temperature into the beam within LCP matrix by a viscous media microextrusion injector.n
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Data
ISSN
2052-4463
e-ISSN
2052-4463
Volume of the periodical
7
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
388
UT code for WoS article
000593909300001
EID of the result in the Scopus database
2-s2.0-85095948049