Controlling cell membrane potential with static nonuniform magnetic fields

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F23%3A00571969" target="_blank" >RIV/68378271:_____/23:00571969 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/chapter/10.1007/978-981-19-8869-1_5" target="_blank" >https://link.springer.com/chapter/10.1007/978-981-19-8869-1_5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-981-19-8869-1_5" target="_blank" >10.1007/978-981-19-8869-1_5</a>

Result language
angličtina
Original language name
Controlling cell membrane potential with static nonuniform magnetic fields
Original language description
The coordinated activity of a myriad of ion channels in a cell is a spectacular biological and physical phenomenon. Understanding mechanisms governing the ion channel gating and setting membrane potentials is key to developing targeted therapeutic strategies using non-contact magnetic stimulations. In this study, we demonstrate theoretically that ion channel activity can be controlled by a static gradient magnetic field. The analysis revealed that specific ion membrane channels can be turned off and on by remotely applying a high gradient magnetic field, thus modulating the cell membrane potentials. The suggested model and mechanisms provide a general framework for identifying possible hidden mechanisms of biomagnetic effects associated with modulation of ion channel activity by high gradient static magnetic fields.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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