Boron-doped diamond electrodes: examining the effect of doping level on the degradation of pharmaceuticals

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F24%3A00597678" target="_blank" >RIV/68378271:_____/24:00597678 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/24:10493031

Result on the web

<a href="https://doi.org/10.1007/s00706-024-03233-0" target="_blank" >https://doi.org/10.1007/s00706-024-03233-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00706-024-03233-0" target="_blank" >10.1007/s00706-024-03233-0</a>

Result language

angličtina

Original language name

Boron-doped diamond electrodes: examining the effect of doping level on the degradation of pharmaceuticals

Original language description

The effect of the boron content doped in the diamond electrode on the oxidative degradation behaviour of the active pharmaceutical ingredient abacavir was investigated. The characteristics of five working boron-doped diamond electrodes, differing in a B/C doping ratio of 500 ppm, 1000 ppm, 2000 ppm, 4000 ppm, and 8000 ppm, were studied. The oxidative degradation of the substance abacavir was studied in a batch cell. The degradation took place under potentiostatic electrolysis at potentials from +0.6 V to +3.7 V. The boron level has a significant effect on the oxidative degradation of the substance at potentials greater than +2.0 V only. Liquid chromatography coupled with mass spectrometry was employed to verify the generation of two primary degradation by-products, namely OP1 (m/z = 319.20) and OP2 (m/z = 247.19). The relative amounts of these degradation products showed variability depending on the diamond electrode used, which was conditioned by different B/C ratios.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Project

<a href="/en/project/GA23-05688S" target="_blank" >GA23-05688S: Electrochemical sensors based on nanostructured and functionalized sp2 and sp3 carbon surfaces for (bio)analytical applications</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Monatshefte fur Chemie

ISSN

0026-9247

e-ISSN

1434-4475

Volume of the periodical

155

Issue of the periodical within the volume

8-9

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

845-850

UT code for WoS article

001275421200004

EID of the result in the Scopus database

2-s2.0-85199350490