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Breaking the DNA by soft X-rays in the water window reveals the scavenging and temporal behaviour of ·OH radicals

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F24%3A00602193" target="_blank" >RIV/68378271:_____/24:00602193 - isvavai.cz</a>

  • Alternative codes found

    RIV/61389005:_____/24:00602193

  • Result on the web

    <a href="https://hdl.handle.net/11104/0360172" target="_blank" >https://hdl.handle.net/11104/0360172</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s41598-024-79328-9" target="_blank" >10.1038/s41598-024-79328-9</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Breaking the DNA by soft X-rays in the water window reveals the scavenging and temporal behaviour of ·OH radicals

  • Original language description

    A laser-plasma source emitting photons with energies in the water window spectral range has been used to reveal the radiation chemical yields of single-strand breaks in plasmid DNA as a function of ·OH radical scavenger concentration. Direct and indirect effects were investigated separately using DNA samples with various levels of hydration. We experimentally determined the value of the efficiency factor for strand cleavage in DNA caused by the reaction with ·OH radicals at 0.11, which was previously found in the theoretical studies. Additionally, the radiation chemical yield of ·OH radicals specific to the water window radiation emission of the source was determined by comparison with the gamma radiation-induced strand break yields. The ·OH radical yield determined using the plasmid DNA samples as a model was similar to the yield found using sensitive fluorescent dosimeters in previous experiments.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10305 - Fluids and plasma physics (including surface physics)

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Scientific Reports

  • ISSN

    2045-2322

  • e-ISSN

    2045-2322

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

    28515

  • UT code for WoS article

    001359321100044

  • EID of the result in the Scopus database

    2-s2.0-85209575100