Diamond-coated quartz crystal microbalance sensors: Challenges in high yield production and enhanced detection of ethanol and sars-cov-2 proteins

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F24%3A00602247" target="_blank" >RIV/68378271:_____/24:00602247 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21230/24:00378517

Result on the web

<a href="https://hdl.handle.net/11104/0359431" target="_blank" >https://hdl.handle.net/11104/0359431</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.matdes.2024.113474" target="_blank" >10.1016/j.matdes.2024.113474</a>

Result language

angličtina

Original language name

Diamond-coated quartz crystal microbalance sensors: Challenges in high yield production and enhanced detection of ethanol and sars-cov-2 proteins

Original language description

This study presents the technological progress in the deposition of diamond thin films on quartz crystal microbalance (QCM) sensors. The linear antenna microwave plasma chemical vapour deposition (CVD) technique effectively grows thin diamond films on QCM substrates (Dia-QCM) differently oriented on the substrate holder in the deposition chamber, resulting in single-sided and double-sided coated QCMs. Each of these coated QCMs offers a distinctive advantage for sensing applications. The double-sided coated QCM sensors exhibited the most effective performance in ethanol detection, demonstrating approx. a 3-fold and 12-fold higher response than single-sided diamond-coated and bare gold QCM sensors, respectively. Furthermore, the single-sided Dia-QCM aptasensors demonstrated superior performance compared to bare gold QCM sensors, with a 2-fold higher response and a lower detection limit for S-RBD protein (LODDia-QCM = 0.09 pg/mL vs. LODAu-QCM = 0.10 pg/mL). In experiments conducted in human plasma, the Dia-QCM aptasensor demonstrated the ability to detect S-RBD protein at concentrations as low as 50 pg/mL, with high percentage recoveries. These results highlight the potential of linear antenna microwave plasma CVD for the mass production of advanced diamond-coated QCM sensors with different diamond film morphologies (porous, micro- or nanocrystalline) for various applications.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20506 - Coating and films

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Materials and Design

ISSN

0264-1275

e-ISSN

1873-4197

Volume of the periodical

248

Issue of the periodical within the volume

Dec

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

113474

UT code for WoS article

001372125700001

EID of the result in the Scopus database

2-s2.0-85210637679