Surface analysis of cannabigerol cocrystals: linking crystal structure to enhanced properties
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F25%3A00618797" target="_blank" >RIV/68378271:_____/25:00618797 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/25:43933250 RIV/60461373:22340/25:43933250
Result on the web
<a href="https://hdl.handle.net/11104/0366525" target="_blank" >https://hdl.handle.net/11104/0366525</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1107/S2052252525001009" target="_blank" >10.1107/S2052252525001009</a>
Alternative languages
Result language
angličtina
Original language name
Surface analysis of cannabigerol cocrystals: linking crystal structure to enhanced properties
Original language description
Cannabigerol is a bioactive compound derived from Cannabis sativa. Its use and research are complicated by its thermally unstable solid form with low solubility and needle habit, preventing easy formulation into tablets or capsules. To overcome these problems, we conducted a crystallization screening with the aim to discover new crystal forms with enhanced properties. Though polymorph and solvate screenings did not yield new forms, the cocrystal screening was successful. Two cocrystals were discovered, one with piperazine and another with tetramethylpirazine, both in a 1:1 ratio. The new solid forms were analysed by a combination of methods, including X-ray powder diffraction, nuclear magnetic resonance spectroscopy, differential scanning calorimetry, thermogravimetric analysis and intrinsic dissolution rate. Single-crystal X-ray diffraction data were used to solve the crystal structures, which were then compared with that of pure CBG.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
IUCrJ
ISSN
2052-2525
e-ISSN
2052-2525
Volume of the periodical
12
Issue of the periodical within the volume
2
Country of publishing house
GB - UNITED KINGDOM
Number of pages
14
Pages from-to
141-154
UT code for WoS article
001437426800003
EID of the result in the Scopus database
2-s2.0-86000489326