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Electronic distraction fixation apparatus stimulates new bone formation in callus

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21110%2F14%3A00216533" target="_blank" >RIV/68407700:21110/14:00216533 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21230/14:00216533 RIV/68407700:21220/14:00216533

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Electronic distraction fixation apparatus stimulates new bone formation in callus

  • Original language description

    Biomechanical loading affects bone structures. The anabolic effects of cyclic biomechanical loading on bone tissue are influenced by the frequency of loading. Mechanotransduction appears to involve a complex interaction between extracellular fluid shearforces and cellular mechanics. Bone cells are activated by both the cyclic fluid shear stresses and transported ions/molecules in fluid flow. The cyclic loading stimulates new bone formation through (for example) integrin linkages and ion channels. Cyclic stress/strain changes in bone and the cyclic fluid flow in intercellular networks can be induced by the dynamic electronic fixative (EDF). The dynamic effects of EDF stimulate the distraction osteogenesis (desmogenesis). Increasing the rate or frequency by which dynamic loading is applied greatly improves bone tissue mechanosensitivity, possibly due to loading-induced extracellular fluid forces around bone cells, that serve as mechanosensors. The elongation of long bones by EDF is acco

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FI - Traumatology and orthopaedics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Pohybové ústrojí. Pokroky ve výzkumu, diagnostice a terapii

  • ISSN

    1212-4575

  • e-ISSN

  • Volume of the periodical

    21

  • Issue of the periodical within the volume

    1-2

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    3

  • Pages from-to

    28-30

  • UT code for WoS article

  • EID of the result in the Scopus database