Cartilage Boundary lubrication ? Theory of self-assembling nanolayers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F13%3A00216682" target="_blank" >RIV/68407700:21220/13:00216682 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Cartilage Boundary lubrication ? Theory of self-assembling nanolayers
Original language description
Articular cartilage has a frictional properties that remains unmatched by industrial joints. The mechanisms by which the synovial joint achieves these properties involve combination of biomechanical and biomolecular factors. Synovial fluid plays multipleroles in joint lubrication by providing a high viscosity "squeeze film" layer that delays cartilage to cartilage contact under compression but also serves as a source of boundary lubricant molecules within the joint. The principles of cartilage lubrication has been studied for many decades, but the exact lubrication mechanism remains unclear. In the last decades, it has been proposed that surface-active phospholipids (SAPL) serve as the major boundary lubricant. Lamellar structures of phospholipids reduce the coeffcient of friction thus lessening wear of the articular surfaces, even under high loads. The aim of this contribution is to propose mechanisms of cartilage lubrication mediated by self-assembling phospholipid layers.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
JJ - Other materials
OECD FORD branch
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Result continuities
Project
<a href="/en/project/TA01010185" target="_blank" >TA01010185: New materials and coatings for joint replacement bionical design</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů