Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F14%3A00217611" target="_blank" >RIV/68407700:21220/14:00217611 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1080/10255842.2014.931078" target="_blank" >http://dx.doi.org/10.1080/10255842.2014.931078</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/10255842.2014.931078" target="_blank" >10.1080/10255842.2014.931078</a>

Result language
angličtina
Original language name
Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella
Original language description
Knowledge of the anisotropic elastic properties of osteon and osteonal lamellae is the key to a description of the elasticity of cortical bone. Various analytical and computational models have been proposed for predicting the mechanical properties of bone at different structural levels. (Hamed et al. 2010) modelled the hierarchical structure of bone at more than one level, using multiple step-by-step micromechanics-based homogenization to capture the behaviour of bone spanning from nano- to sub- microstructure levels. A feature of our model is that we have developed an inverse homogenization scheme from the macroscopic scale of cortical bone to the single lamella level. There are also experimental methods for studies of cortical bone at the level of osteon and osteonal lamella, e.g. instrumented nanoindentation (Lukes et al. 2009), atomic force microscopy (Lefevre et al. 2013) and the ultrasound method (Rho 1996). To validate the mathematical model presented here, we determined the mechanical properties of a single lamella in three perpendicular directions using instrumented nanoindentation.
Czech name
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Czech description
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Project
<a href="/en/project/TA01010185" target="_blank" >TA01010185: New materials and coatings for joint replacement bionical design</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Computer Methods in Biomechanics and Biomedical Engineering
ISBN
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ISSN
1025-5842
e-ISSN
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Number of pages
2
Pages from-to
24-25
Publisher name
Taylor & Francis
Place of publication
London
Event location
Valenciennes
Event date
Aug 27, 2014
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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