Influence of surface roughness of carbon materials on human osteoblast-like cell growth

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F14%3A00218358" target="_blank" >RIV/68407700:21220/14:00218358 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/14:00428950
Result on the web
<a href="http://dx.doi.org/10.1002/jbm.a.34833" target="_blank" >http://dx.doi.org/10.1002/jbm.a.34833</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jbm.a.34833" target="_blank" >10.1002/jbm.a.34833</a>

Result language
angličtina
Original language name
Influence of surface roughness of carbon materials on human osteoblast-like cell growth
Original language description
This article presents a study of the dependence of the biocompatibility of a carbon-based material, namely a 2D C/C composite, on mechanical and chemical surface modifications. The mechanical modifications were surface grinding and polishing, and chemical modifications were made by depositing thin layers of pyrolytic carbon, titanium-carbon and DLC layers. Human osteoblast-like MG 63 cells were cultivated on these materials. The densities of the cells after one-day cultivation and after four-day cultivation, and the average cell spreading area after one-day cultivation, were evaluated in dependence on particular surface roughness parameters. The minima of the cell density on pyrolytic carbon and titanium-carbon layers were found; they were connected with the maxima of the average cell area. For DLC, the cell area decreased as the roughness parameter Ra increased in the range 0.1-10 mu m, although the minimum appeared for the density of the cells. Using a multivariate test, the dependen
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JJ - Other materials
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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