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Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F06%3A03117834" target="_blank" >RIV/68407700:21230/06:03117834 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Summarizing gene-expression-based classifiers by meta-mining comprehensible relational patterns

  • Original language description

    We propose a methodology for predictive classification from gene expression data, able to combine the robustness of high-dimensional statistical classification methods with the comprehensibility and interpretability of simple logic-based models. We firstconstruct a robust classifier combining contributions of a large number of gene expression values, and then (meta)-mine the classifier for compact summarizations of subgroups among genes associated with a given class therein. The subgroups are describedby means of relational logic features extracted from publicly available gene ontology information. The curse of dimensionality pertaining to the gene expression based classification problem due to the large number of attributes (genes) is turned into anadvantage in the secondary, meta-mining task as here the original attributes become learning examples.

  • Czech name

    Není k dispozici

  • Czech description

    Není k dispozici

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    JC - Computer hardware and software

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Proceedings of the Fourth IASTED International Conference on BIOMEDICAL ENGINEERING

  • ISBN

    0-88986-576-0

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    19-24

  • Publisher name

    Acta Press

  • Place of publication

    Zürich

  • Event location

    Innsbruck

  • Event date

    Feb 15, 2006

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article