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Independent-Component-Analysis-Based Spike Sorting Algorithm for High-Density Microelectrode Array Data Processing

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F09%3A00158838" target="_blank" >RIV/68407700:21230/09:00158838 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Independent-Component-Analysis-Based Spike Sorting Algorithm for High-Density Microelectrode Array Data Processing

  • Original language description

    Microelectrode arrays (MEAs) become an important tool for neurophysiology research. They are instrumental in revealing neural network formation processes and inter-cell communication schemes, which helps to understand the functioning of the human brain and to treat it's diseases. The electrode pitch of current CMOS-based MEAs can be as low as 18 ?m, which allows for recording the activity of single cells simultaneously on several channels [1]. Each electrode in turn records the activity of several adjacent neurons. The presented algorithm employs Independent Component Analysis (ICA) method to recover the spike signals and to assign them to a particular neuron. To overcome the fundamental ICA requirement of linearly mixed independent sources, which is not satisfied in the case of neuronal recordings, the algorithm runs in a loop, successively extracts traces with spiking activity, overlays those with previously detected ones and assigns signals to individual neurons.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    JB - Sensors, detecting elements, measurement and regulation

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GD102%2F09%2FH082" target="_blank" >GD102/09/H082: Sensors and intelligent sensor systems</a><br>

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    IEEE SENSORS 2009 - The Eighth IEEE Conference on Sensors

  • ISBN

    978-1-4244-5335-1

  • ISSN

    1930-0395

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

  • Publisher name

    IEEE Sensors Council

  • Place of publication

    Christchurch

  • Event location

    Christchurch

  • Event date

    Oct 25, 2009

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article