Microwave Applicator for Hyperthermia Treatment on in Vivo Melanoma Model

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F10%3A00161903" target="_blank" >RIV/68407700:21230/10:00161903 - isvavai.cz</a>

Alternative codes found

RIV/61388971:_____/10:00350314

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Microwave Applicator for Hyperthermia Treatment on in Vivo Melanoma Model

Original language description

This work evaluates a planar microwave applicator for in vivo superficial hyperthermia treatments on small tumors in the mouse mimicking treatments for human neoplasms. The design of the applicator, was challenged by the small dimensions of the tumors and unwanted diffusion of heating in the tumor-bearing animals. The study was firstly performed by simulations of SAR distribution inside a homogeneous phantom, considering an integrated water bolus. Further tests were performed on homogeneous agar phantomto simulate the temperature distribution in the biological tissue and to assess the possible modality and schedule of hyperthermia delivery. The in vivo experiments showed the evidence of microwave-induced heating and damage of the melanoma tissue in arange of penetration coherent both with simulations and phantom studies. This approach appears perspective for designing limited microwave-delivery applicators for treatments of human superficial tumors and pre-tumoral les

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Medical and Biological Engineering and Computing

ISSN

0140-0118

e-ISSN

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Volume of the periodical

48

Issue of the periodical within the volume

3

Country of publishing house

AT - AUSTRIA

Number of pages

8

Pages from-to

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UT code for WoS article

000275135300009

EID of the result in the Scopus database

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