Repetitive TMS of the somatosensory cortex improves writer's cramp and enhances cortical activity

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F10%3A00168876" target="_blank" >RIV/68407700:21230/10:00168876 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/10:6832 RIV/00064165:_____/10:6832

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Repetitive TMS of the somatosensory cortex improves writer's cramp and enhances cortical activity

Original language description

We focused on the modulation of the primary somatosensory cortex (SI) induced by repetitive transcranial magnetic stimulation (rTMS) in order to improve symptoms of writer's cramp. Patients with writer's cramp were treated with 30-minute 1 Hz real- or sham-rTMS of the SI cortex every day for 5 days. 1.5 T fMRI was examined during simple hand movements. While in the pilot study the rTMS coil was navigated over the SI cortex, patients in the advanced study had the coil above the postcentral sulcus. Afterreal-rTMS, 4 pilot study patients and 10 advanced study patients experienced subjective and objective improvement in writing. Patients exhibited a rTMS-induced BOLD signal increase bilaterally in the SI cortex, posterior parietal cortex and in the supplementary motor area (P<0.001 corrected). After sham-rTMS, no BOLD signal changes were observed. In conclusion, 1 Hz rTMS of the SI cortex can improve writer's cramp while increasing the cortical activity in both hemispheres.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/1M0567" target="_blank" >1M0567: Centre for Applied Cybernetics</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

31

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

14

Pages from-to

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UT code for WoS article

000288581900011

EID of the result in the Scopus database

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