Inactivation of prions using electrical DC discharges at atmospheric pressure and ambient temperature
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F10%3A00176471" target="_blank" >RIV/68407700:21230/10:00176471 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Inactivation of prions using electrical DC discharges at atmospheric pressure and ambient temperature
Original language description
Prion proteins are cellular membrane-bound glycoproteins. In the prevalent ?-helix conformation called PrPC, they are common proteinaceous constituents of mammalian cells. However, if misfolded into the ?-sheet conformation called PrPSc, they cause incurable and lethal neurodegenerative diseases (transmissible spongiform encephalopaties), referred to as scrapie, Creutzfeldt-Jakob disease, bovine spongiform encephalopathy etc. In general, prions are higly resistant to proteases and common sterilization procedures.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů