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Inactivation of prions using electrical DC discharges at atmospheric pressure and ambient temperature

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F10%3A00176471" target="_blank" >RIV/68407700:21230/10:00176471 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Inactivation of prions using electrical DC discharges at atmospheric pressure and ambient temperature

  • Original language description

    Prion proteins are cellular membrane-bound glycoproteins. In the prevalent ?-helix conformation called PrPC, they are common proteinaceous constituents of mammalian cells. However, if misfolded into the ?-sheet conformation called PrPSc, they cause incurable and lethal neurodegenerative diseases (transmissible spongiform encephalopaties), referred to as scrapie, Creutzfeldt-Jakob disease, bovine spongiform encephalopathy etc. In general, prions are higly resistant to proteases and common sterilization procedures.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů