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Can We Generate Systemic Arterial Hypertension by Pulsatile LVAD in Our Patients?

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F11%3A00186583" target="_blank" >RIV/68407700:21230/11:00186583 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Can We Generate Systemic Arterial Hypertension by Pulsatile LVAD in Our Patients?

  • Original language description

    On the basis of our personal experience of studying co-temporary scientific articles and the modelling of flow and pressure patterns in systemic vascular beds, we are encouraged to claim, that extremely small patients can experience systemic arterial hypertension generated by pulsatile a left ventricular assist device (LVAD. After implantation of LVAD with the same stroke volume (65ml), all patients have the same average flow during the ejection period, i.e. 65ml for 300ms (13 l/min!). The average flowfor the ejection period, the average blood flow during the ejection period through the entire systemic vascular bed is higher in non-physiological terms for extremely small patients and may cause iatrogenic systemic arterial hypertension. In addition wesuppose a large "stroke mismatch" (large disproportion between the primary stroke volume and the artificial one) could cause unexpected events like brain bleed

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    JC - Computer hardware and software

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů