Cu/Ag Nanoparticle-Based Surface-Enhanced Raman Scattering Substrates for Label-Free Bacterial Detection
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F22%3A00359895" target="_blank" >RIV/68407700:21230/22:00359895 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1021/acsanm.2c02571" target="_blank" >https://doi.org/10.1021/acsanm.2c02571</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsanm.2c02571" target="_blank" >10.1021/acsanm.2c02571</a>
Alternative languages
Result language
angličtina
Original language name
Cu/Ag Nanoparticle-Based Surface-Enhanced Raman Scattering Substrates for Label-Free Bacterial Detection
Original language description
Surface-enhanced Raman spectroscopy (SERS) is a promising analytical technique for fast and accurate disease detection due to its attractive features. However, realizing label-free direct detection is still challenging as most probes have extremely low Raman cross sections and little affinity to SERS substrates. Disappointingly, SERS spectra of most bacteria and other biological samples look similar as the differences in their molecular compositions are subtle and not detectable. Hence, the fabrication of highly enhancing plasmonic nanoparticles with excellent uniformity is demanded. Moreover, as SERS substrates are not reusable, cost-effective and simplistic fabrication methods are critical. Here, we report a facile approach to synthesizing Ag nanoparticle array on Cu-foil in less than 3 min, using only Cu-foil, silver nitrate, and hydroquinone. We employed the idea of galvanic replacement in combination with a seed mediated particle-growth approach. The label-free bacterial detection has shown that our Cu/Ag nanoparticle substrate is superior to highly acclaimed Ag nanocubes. Creating strong second and third-generation SERS hot-spots through cooperative interaction of homo-(Ag-Ag) and heterogeneous (Ag-Cu) surfaces contributes mainly to the observed excellent enhancement. Interestingly, direct liquid bacteria sample analysis showed a 6-fold higher detection sensitivity than completely dried samples. We believe that our approach will offer remarkable advantages and change how SERS substrates are prepared and conducted in SERS-based bacterial detection.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ACS Applied Nano Materials
ISSN
2574-0970
e-ISSN
2574-0970
Volume of the periodical
5
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
11567-11576
UT code for WoS article
000841239500001
EID of the result in the Scopus database
2-s2.0-85136472024