Speech and gait abnormalities in motor subtypes of de-novo Parkinson's disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F23%3A00367040" target="_blank" >RIV/68407700:21230/23:00367040 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21460/23:00367040 RIV/00216208:11110/23:10458845 RIV/00216208:11310/23:10458845 RIV/00064165:_____/23:10458845
Result on the web
<a href="https://doi.org/10.1111/cns.14158" target="_blank" >https://doi.org/10.1111/cns.14158</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/cns.14158" target="_blank" >10.1111/cns.14158</a>
Alternative languages
Result language
angličtina
Original language name
Speech and gait abnormalities in motor subtypes of de-novo Parkinson's disease
Original language description
AimTo investigate the presence and relationship of temporal speech and gait parameters in patients with postural instability/gait disorder (PIGD) and tremor-dominant (TD) motor subtypes of Parkinson's disease (PD). MethodsSpeech samples and instrumented walkway system assessments were acquired from a total of 60 de-novo PD patients (40 in TD and 20 in PIGD subtype) and 40 matched healthy controls. Objective acoustic vocal assessment of seven distinct speech timing dimensions was related to instrumental gait measures including velocity, cadence, and stride length. ResultsCompared to controls, PIGD subtype showed greater consonant timing abnormalities by prolonged voice onset time (VOT) while also shorter stride length during both normal walking and dual task, while decreased velocity and cadence only during dual task. Speaking rate was faster in PIGD than TD subtype. In PIGD subtype, prolonged VOT correlated with slower gait velocity (r = -0.56, p = 0.01) and shorter stride length (r = -0.59, p = 0.008) during normal walking, whereas relationships were also found between decreased cadence in dual task and irregular alternating motion rates (r = -0.48, p = 0.04) and prolonged pauses (r = -0.50, p = 0.03). No correlation between speech and gait was detected in TD subtype. ConclusionOur findings suggest that speech and gait rhythm disorder share similar underlying pathomechanisms specific for PIGD subtype.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30210 - Clinical neurology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
CNS Neuroscience and Therapeutics
ISSN
1755-5930
e-ISSN
1755-5949
Volume of the periodical
29
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
2101-2110
UT code for WoS article
000953661700001
EID of the result in the Scopus database
2-s2.0-85150882634