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DynMap : mapping short reads to multiple related genomes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21240%2F11%3A00188300" target="_blank" >RIV/68407700:21240/11:00188300 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DynMap : mapping short reads to multiple related genomes

  • Original language description

    The constant advances in sequencing technology have redefined the way genome sequencing is performed. They are able to produce millions of short sequences (reads) during a single experiment, and with a much lower cost than previously possible. Due to thedramatic increase in the amount of data generated, efficient algorithms for aligning (mapping) these reads to reference genomes are in great demand, and recently, there has been ample work for publishing such algorithms. In this paper, we study a different version of this problem; mapping these reads to multiple related genomes (e.g. individuals of the same species). We present DynMap, a new practical algorithm, which employs a suitable data structure that takes into account potential inherent genomicvariability (replacements, insertions, deletions) between related genomes. Therefore, if a small number of differences occurs within a reference sequence, the already mapped reads can be altered dynamically. The presented experimental res

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    IN - Informatics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA201%2F09%2F0807" target="_blank" >GA201/09/0807: String and tree analysis and processing</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    ACM BCB 2011: ACM Conference on Bioinformatics, Computational Biology and Biomedicine

  • ISBN

    978-1-4503-0796-3

  • ISSN

  • e-ISSN

  • Number of pages

    5

  • Pages from-to

    330-334

  • Publisher name

    ACM

  • Place of publication

    New York

  • Event location

    Chicago

  • Event date

    Aug 1, 2011

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article