Mapping Short Reads to a Genomic Sequence with Circular Structure

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21240%2F12%3A00188306" target="_blank" >RIV/68407700:21240/12:00188306 - isvavai.cz</a>

Result on the web

<a href="http://www.igi-global.com/article/international-journal-systems-biology-biomedical/63044" target="_blank" >http://www.igi-global.com/article/international-journal-systems-biology-biomedical/63044</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4018/ijsbbt.2012010103" target="_blank" >10.4018/ijsbbt.2012010103</a>

Result language

angličtina

Original language name

Mapping Short Reads to a Genomic Sequence with Circular Structure

Original language description

Constant advances in DNA sequencing technologies are turning whole-genome sequencing into a routine procedure, resulting in massive amounts of data that need to be processed. Tens of gigabytes of data, in the form of short sequences (reads), need to be mapped back onto reference sequences, a few gigabases long. A first generation of short-read alignment algorithms successfully employed hash tables, and the current second generation uses the Burrows-Wheeler transform, further improving speed and memory footprint. These next-generation sequencing technologies allow researchers to characterise a bacterial genome, during a single experiment, at a moderate cost. In this article, as most of the bacterial chromosomes contain a circular DNA molecule, the authors present a new simple, yet efficient, sensitive and accurate algorithm, specifically designed for mapping millions of short reads to a genomic sequence with circular structure.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

IN - Informatics

OECD FORD branch

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Project

<a href="/en/project/GA201%2F09%2F0807" target="_blank" >GA201/09/0807: String and tree analysis and processing</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Systems Biology and Biomedical Technologies

ISSN

2160-9586

e-ISSN

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Volume of the periodical

2012

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

26-34

UT code for WoS article

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EID of the result in the Scopus database

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