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Influence of crystallinity on bio-physical properties of hydroxapatite films

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F08%3A12148471" target="_blank" >RIV/68407700:21460/08:12148471 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Influence of crystallinity on bio-physical properties of hydroxapatite films

  • Original language description

    Crystalline and amorphous hydroxapatite (HA) films were prepared by KrF pulsed laser deposition method. Influence of HA structure on biomedical properties was studied. Crystallinity, morphology, composition, optical transmission and mechanical properties(adhesion) were measured. Biomedical properties were tested using human dermal fibroblast. The specific proteins (vimentin, fibronectin, pankeratin, keratin 14) were visualized. The worst proliferation of fibroblasts was observed on the amophous coating, whereas the adhesion was well comparable with other surfaces. The level of keratinocyte differentiation on the amorphous and crystalline HA coating was the same. Results reached on physical and mechanical properties are discussed in connection with results of in vitro tests.

  • Czech name

    Vliv krystalihity na biofyzikální vlastnosti tenkých vrstev hydroxyapatitu

  • Czech description

    Krystalické a amorfní HA filmy byly připraveny KrF pulsní laserovou depozicí. Byl studován vliv struktur HA na biomedicínské vlastnosti. Byla změřena krystalinita, morfologie, kompozice, optická transmise a mechanické vlastnosti (adheze). Biomedicínské vlastností byly testovány použitím lidských dermálních fibroplastů. Vysledky, dosaženy v oblasti fyzikálních a mechanických vlastností byly diskutovány ve spojitosti s vysledky in vitro testů.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    BH - Optics, masers and lasers

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    4th Kuala Lumpur International Conference on Biomedical Engineering

  • ISBN

    978-3-540-69139-6

  • ISSN

    1680-0737

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

  • Publisher name

    Springer

  • Place of publication

    Heidelberg

  • Event location

    Kuala Lumpur

  • Event date

    Jun 25, 2008

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article