Study of the DBS STN Effect on Parkinson's Disease Finger Tapping Using NIRS

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F16%3A00307097" target="_blank" >RIV/68407700:21460/16:00307097 - isvavai.cz</a>

Result on the web

<a href="http://hb2016.fbmi.cvut.cz" target="_blank" >http://hb2016.fbmi.cvut.cz</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Study of the DBS STN Effect on Parkinson's Disease Finger Tapping Using NIRS

Original language description

Near-infrared spectroscopy (NIRS) of brain function employs low-energy optical radiation for measuring absorption changes in sub-surface tissues, in order to infer local concentration changes of oxy- and de-oxyhemoglobin as correlates of functional brain activity. To achieve brain activity spatial mapping, arrays of multiple source-detector pairs are placed over the area of interest. The aim of this study is to evaluate differences in brain activity, caused by level of deep brain stimulation of subthalamic nucleus (DBS STN), during finger tapping (FT) task of patients with Parkinson's disease (PD). DBS STN is a procedure used to treat PD symptoms (essential tremor and dystonia). Brain activity of specific area is represented by extracted value parameter from NIRS signal. Individual measurements were done at the Department of Neurology, First Medical Faculty in Prague. Clinical set consisted of left and right hand FT examination for every patient (N = 9). All measurements were performed on NIRSport device, comprising 7 sources and 8 detectors. Differences in activities in the individual areas of the brain during stimulation and without stimulation were tested by the nonparametric Wilcoxon paired test. Statistically significant differences (at alpha = 0,05) of FT right hand were reached in the primary motor cortex (M1), in the supplementary motor area (SMA) and in the premotor cortex (PM). Therefore, in fields related to planning and executing motion.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

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OECD FORD branch

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Project

<a href="/en/project/NV16-28119A" target="_blank" >NV16-28119A: Analysis of movement disorders for the study of extrapyramidal diseases mechanisms using motion capture camera systems</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

16th Conference on Human Biomechanics 2016 – Conference proceedings

ISBN

9788001060391

ISSN

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e-ISSN

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Number of pages

2

Pages from-to

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Publisher name

Faculty of biomedical engineering, Department of Natural sciences

Place of publication

Kladno

Event location

Kladno

Event date

Nov 7, 2016

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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