Standardization of patient modeling in hyperthermia simulation studies: introducing the Erasmus Virtual Patient Repository

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F20%3A00341613" target="_blank" >RIV/68407700:21460/20:00341613 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1080/02656736.2020.1772996" target="_blank" >https://doi.org/10.1080/02656736.2020.1772996</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/02656736.2020.1772996" target="_blank" >10.1080/02656736.2020.1772996</a>

Result language

angličtina

Original language name

Standardization of patient modeling in hyperthermia simulation studies: introducing the Erasmus Virtual Patient Repository

Original language description

Purpose: Thermal dose-effect relations have demonstrated that clinical effectiveness of hyperthermia would benefit from more controlled heating of the tumor. Hyperthermia treatment planning (HTP) is a potent tool to study strategies enabling target conformal heating, but its accuracy is affected by patient modeling approximations. Homogeneous phantoms models are being used that do not match the body shape of patients in treatment position and often have unrealistic target volumes. As a consequence, simulation accuracy is affected, and performance comparisons are difficult. The aim of this study is to provide the first step toward standardization of HTP simulation studies in terms of patient modeling by introducing the Erasmus Virtual Patient Repository (EVPR): a virtual patient model database. Methods: Four patients with a tumor in the head and neck or the pelvis region were selected, and corresponding models were created using a clinical segmentation procedure. Using the Erasmus University Medical Center standard procedure, HTP was applied to these models and compared to HTP for commonly used surrogate models. Results: Although this study was aimed at presenting the EVPR database, our study illustrates that there is a non-negligible difference in the predicted SAR patterns between patient models and homogeneous phantom-based surrogate models. We further demonstrate the difference between actual and simplified target volumes being used today. Conclusion: Our study describes the EVPR for the research community as a first step toward standardization of hyperthermia simulation studies.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20201 - Electrical and electronic engineering

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Hyperthermia

ISSN

0265-6736

e-ISSN

1464-5157

Volume of the periodical

37

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

608-616

UT code for WoS article

000549025600001

EID of the result in the Scopus database

2-s2.0-85086297990