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In Vitro Estimation of Relative Compliance during High-Frequency Oscillatory Ventilation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F21%3A00346480" target="_blank" >RIV/68407700:21460/21:00346480 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.3390/app11030899" target="_blank" >https://doi.org/10.3390/app11030899</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/app11030899" target="_blank" >10.3390/app11030899</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    In Vitro Estimation of Relative Compliance during High-Frequency Oscillatory Ventilation

  • Original language description

    High-frequency oscillatory ventilation (HFOV), which uses a small tidal volume and a high respiratory rate, is considered a type of protective lung ventilation that can be beneficial for certain patients. A disadvantage of HFOV is its limited monitoring of lung mechanics, which complicates its settings and optimal adjustment. Recent studies have shown that respiratory system reactance (Xrs) could be a promising parameter in the evaluation of respiratory system mechanics in HFOV. The aim of this study was to verify in vitro that a change in respiratory system mechanics during HFOV can be monitored by evaluating Xrs. We built an experimental system consisting of a 3100B high-frequency oscillatory ventilator, a physical model of the respiratory system with constant compliance, and a system for pressure and flow measurements. During the experiment, models of different constant compliance were connected to HFOV, and Xrs was derived from the impedance of the physical model that was calculated from the spectral density of airway opening pressure and spectral cross-power density of gas flow and airway opening pressure. The calculated Xrs changed with the change of compliance of the physical model of the respiratory system. This method enabled monitoring of the trend in the respiratory system compliance during HFOV, and has the potential to optimize the mean pressure setting in HFOV in clinical practice.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20601 - Medical engineering

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Applied Sciences

  • ISSN

    2076-3417

  • e-ISSN

    2076-3417

  • Volume of the periodical

    11

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    9

  • Pages from-to

    1-9

  • UT code for WoS article

    000614985600001

  • EID of the result in the Scopus database

    2-s2.0-85099907472