Assessment of Respiratory System Resistance during High-Frequency Oscillatory Ventilation Based on In Vitro Experiment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F21%3A00354316" target="_blank" >RIV/68407700:21460/21:00354316 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.3390/app112311279" target="_blank" >https://doi.org/10.3390/app112311279</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/app112311279" target="_blank" >10.3390/app112311279</a>
Alternative languages
Result language
angličtina
Original language name
Assessment of Respiratory System Resistance during High-Frequency Oscillatory Ventilation Based on In Vitro Experiment
Original language description
High-frequency oscillatory ventilation (HFOV) is a type of mechanical ventilation with a protective potential characterized by a small tidal volume. Unfortunately, HFOV has limited monitoring of ventilation parameters and mechanical parameters of the respiratory system, which makes it difficult to adjust the continuous distension pressure (CDP) according to the individual patient's airway status. Airway resistance R-aw is one of the important parameters describing the mechanics of the respiratory system. The aim of the presented study was to verify in vitro whether the resistance of the respiratory system R-rs can be reliably determined during HFOV to evaluate R-aw in pediatric and adult patients. An experiment was performed with a 3100B high-frequency oscillator, a physical model of the respiratory system, and a pressure and flow measurement system. The physical model with different combinations of resistance and compliance was ventilated during the experiment. The resistance R-rs was calculated from the impedance of the physical model, which was determined from the spectral density of the pressure at airway opening and the spectral cross-density of the gas flow and pressure at airway opening. R-rs of the model increased with an added resistor and did not change significantly with a change in compliance. The method is feasible for monitoring respiratory system resistance during HFOV and has the potential to optimize CDP settings during HFOV in clinical practice.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20601 - Medical engineering
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Sciences
ISSN
2076-3417
e-ISSN
2076-3417
Volume of the periodical
11
Issue of the periodical within the volume
23
Country of publishing house
CH - SWITZERLAND
Number of pages
8
Pages from-to
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UT code for WoS article
000734772000001
EID of the result in the Scopus database
2-s2.0-85120321461