Test of complex nanostructures as gene delivery system to cardiac cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F21%3A00357303" target="_blank" >RIV/68407700:21460/21:00357303 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26220/20:PU137839
Result on the web
<a href="http://dx.doi.org/10.37904/nanocon.2020.3757" target="_blank" >http://dx.doi.org/10.37904/nanocon.2020.3757</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.37904/nanocon.2020.3757" target="_blank" >10.37904/nanocon.2020.3757</a>
Alternative languages
Result language
angličtina
Original language name
Test of complex nanostructures as gene delivery system to cardiac cells
Original language description
Various nanostructures, including liposomes, dendrimers, polymers, carbon or silicon materials, and metal nanoparticles seems to be evaluated as carriers in different gene delivery systems. Muscle cells are target of modern gene medicine, due to of the much pathology (arrhythmias, channels pathological mutation, abnormal apoptosis) with limited curability by traditional drugs. The zeta potential of the muscle cells were identified by non-traditional method of DLS. This was starting point to setting of parameters for experimental liposome, the liposome surface charge have been tested and modified by cationic plasmid and final complex was evaluated as delivery system of DNA into the muscle cardiac cells
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
Result continuities
Project
<a href="/en/project/FW01010106" target="_blank" >FW01010106: Development of new generation medical devices by means of the translational medicine and physical interventions principle</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
NANOCON Conference Proceedings - International Conference on Nanomaterials
ISBN
978-80-87294-98-7
ISSN
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e-ISSN
2694-930X
Number of pages
5
Pages from-to
342-346
Publisher name
TANGER
Place of publication
Ostrava
Event location
Brno
Event date
Oct 21, 2020
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000664505500058