Significant decrease of methemoglobin and carboxyhemoglobin during short-time hypoxic breathing experiment in simulated avalanche snow

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F22%3A00358029" target="_blank" >RIV/68407700:21460/22:00358029 - isvavai.cz</a>

Result on the web

<a href="http://poseidon2.feld.cvut.cz/conf/poster/proceedings/POSTER_2022.pdf" target="_blank" >http://poseidon2.feld.cvut.cz/conf/poster/proceedings/POSTER_2022.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Significant decrease of methemoglobin and carboxyhemoglobin during short-time hypoxic breathing experiment in simulated avalanche snow

Original language description

Current modern pulse oximeters allow noninvasive monitoring of dysfunctional forms of hemoglobin. The concentrations of Methemoglobin (MetHb) and Carboxyhemoglobin (COHb) indicate the state of the organism, but the accuracy of the measurement of these parameters may be reduced during hypoxia. The aim of the study was to determine the effect of the decrease of peripheral oxygen saturation (SpO2) on measured concentrations of MetHb and COHb during short-time breathing experiments with simulated avalanche snow accompanied by a rapid onset of hypoxemia. Thirteen volunteers (age 22.4 ± 1.3 years, weight 78.1 ± 10.1 kg) underwent a breathing experiment into perlite as a surrogate of avalanche snow. Rapid onset of hypoxemia and hypercapnia occurred while MetHb, COHb, and SpO2 were measured continuously by a monitor of oxygenation Masimo Root (Masimo Corporation, Irwine, CA). On average, the measured MetHb concentration decreased to 50 % at the end of the breathing trial (lowest SpO2 values) compared to the stabilization phase. COHb concentrations were even three times lower than in the stabilization phase. Although the measured decrease in both parameters was significant, the authors speculate that it is caused by the decreased accuracy of detection system of pulse oximeter. SpO2 concentrations should also be considered when determining MetHb and COHb concentrations using pulse oximeter.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

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OECD FORD branch

20601 - Medical engineering

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Proceedings of the International Student Scientific Conference Poster – 26/2022

ISBN

978-80-01-06992-9

ISSN

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e-ISSN

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Number of pages

4

Pages from-to

52-55

Publisher name

Fakulta elektrotechnická

Place of publication

Praha

Event location

Praha

Event date

May 12, 2022

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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