All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

The Effect of Poly-E-Caprolactone Nanofibers with Platelets on Cell Proliferation and Viability In:

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21720%2F19%3A00339928" target="_blank" >RIV/68407700:21720/19:00339928 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The Effect of Poly-E-Caprolactone Nanofibers with Platelets on Cell Proliferation and Viability In:

  • Original language description

    Platelets are effective source of growth factors and other bioactive molecules. They can be combined with an appropriate scaffold where the mechanical properties of the scaffold and bioactive properties of platelets modulate cell behavior in the site of the injury. In this study, we compared different concentrations of platelets adhered on PCL nanofibers and evaluated their effect on mouse 3T3 fibroblasts. Platelets in maximum concentration significantly stimulated the viability when it is compared with control. Proliferation of fibroblasts was significantly higher than in the control group cultured on the plain scaffolds. Cells were well- spread on the scaffolds with adhered platelets, whereas on the plain scaffolds, the cells created clusters. The effect of platelets was dose-dependent. It is obvious, that the combination of bioactive substances and PLC nanofibres significantly stimulates cells growth and metabolic activity of the tested cell type.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    30212 - Surgery

Result continuities

  • Project

    <a href="/en/project/NV17-32285A" target="_blank" >NV17-32285A: Functionalized nanofibers for prevention of incisional hernia formation</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    10TH ANNIVERSARY INTERNATIONAL CONFERENCE ON NANOMATERIALS - RESEARCH & APPLICATION (NANOCON 2018)

  • ISBN

    978-80-87294-89-5

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    477-482

  • Publisher name

    TANGER

  • Place of publication

    Ostrava

  • Event location

    Brno

  • Event date

    Oct 17, 2018

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000513131900083