Optimization of biodegradable polymeric submicroparticles preparation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F11%3A43866347" target="_blank" >RIV/70883521:28110/11:43866347 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/11:43866347
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Optimization of biodegradable polymeric submicroparticles preparation
Original language description
The influence of various surfactants and their combinations on the particle diameter and particles size distribution during their preparation from biodegradable poly(lactide acid) by the method of emulsification and solvent evaporation at reduced pressure was investigated. The attention was focused on the possibility to control the size of resultant particles by hydrophilic-lipophilic balance parameter (HLB), which is a characteristic of nonionic surfactants. First, nonionic surfactants were combined toobtain various HLB values of the system and then combinations with the biodegradable surface active polymer Gelatin A were assayed. Gelatin A proved to be a suitable emulsion stabilizer in the process of PLA submicroparticles preparation and it was found that to achieve PLA submicroparticles with the lowest diameter and narrow distribution HLB of the system has to be set up under about 16. For combinations of gelatin A and another nonionic surfactant the reduction of the aggregate HLB v
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Recent Researches in Geography, Geology, Energy, Environment and Biomedicine - Proc. of the 4th WSEAS Int. Conf. on EMESEG'11, 2nd Int. Conf. on WORLD-GEO'11, 5th Int. Conf. on EDEB'11
ISBN
978-1-61804-022-0
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
294-299
Publisher name
WSEAS Press (GR)
Place of publication
Rhodes
Event location
Corfu Island
Event date
Jul 14, 2011
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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