Low molecular weight poly(lactic acid) microparticles for controlled release of the herbicide metazachlor: Preparation, morphology, and release kinetics

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F12%3A43867835" target="_blank" >RIV/70883521:28110/12:43867835 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/12:43867835
Result on the web
<a href="http://dx.doi.org/10.1021/jf300521j" target="_blank" >http://dx.doi.org/10.1021/jf300521j</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jf300521j" target="_blank" >10.1021/jf300521j</a>

Result language
angličtina
Original language name
Low molecular weight poly(lactic acid) microparticles for controlled release of the herbicide metazachlor: Preparation, morphology, and release kinetics
Original language description
The preemergence chloroacetamide herbicide metazachlor was encapsulated in biodegradable low molecular weight poly(lactic acid) micro- and submicroparticles, and its release to the water environment was investigated. Three series of particles, S, M, andL, varying in their size (from 0.6 to 8 ?m) and with various initial amounts of the active agent (5%, 10%, 20%, 30% w/w) were prepared by the oil-in-water solvent evaporation technique with gelatin as biodegradable surfactant. The encapsulation efficiencies reached were about 60% and appeared to be lower for smaller particles. Generally, it was found that the rate of herbicide release decreased with increasing size of particles. After 30 days the portions of the herbicide released for its highest loading (30% w/w) were 92%, 56%, and 34% for about 0.6, 0.8, and 8 ?m particles, respectively. The release rates were also lower for lower herbicide loadings. Metazachlor release from larger particles tended to be a diffusion-controlled process
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JJ - Other materials
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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