Influence of self-organized fluid flows on secondary and tertiary structure of bio-macromolecular system

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F17%3A63510508" target="_blank" >RIV/70883521:28110/17:63510508 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/17:63510508
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Influence of self-organized fluid flows on secondary and tertiary structure of bio-macromolecular system
Original language description
Spatial arrangement of bio-macromolecular systems affects their function and role in physiological processes, as is generally known. The modification of the secondary and tertiary structure of the given system occurs due to the changes of temperature, pH, ionic strength, shear forces, etc. In this work is presented a new approach enabling initiation the changes of secondary and tertiary structure of the macromolecular system in the solution without modification the pH or ionic strength of the system. For this purpose is used the self-organized fluid flow in the form of Bénard-Marangoni convective instability. The result of continuously repeating the uneven shear strain of macromolecules in organized flowing solution is the change of mean coil size, its thermal stability and self-organizing capabilities, manifested through the changes in the surface activity at the interfaces or during the formation of self-supporting polymeric film. These changes can have significant implications, for example in producing smooth thin foils for medicinal application.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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