Hydration and barrier properties of emulsions with the addition of keratin hydrolysate

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F18%3A63520468" target="_blank" >RIV/70883521:28110/18:63520468 - isvavai.cz</a>

Alternative codes found

RIV/70883521:28140/18:63520468

Result on the web

<a href="http://dx.doi.org/10.3390/cosmetics5040064" target="_blank" >http://dx.doi.org/10.3390/cosmetics5040064</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/cosmetics5040064" target="_blank" >10.3390/cosmetics5040064</a>

Result language

angličtina

Original language name

Hydration and barrier properties of emulsions with the addition of keratin hydrolysate

Original language description

Although keratin hydrolysates (KH) are added to skin care agents, detailed studies on the moisturising effects of KH are lacking. The aim of this study is to test whether adding KH into an ointment base (OB) heighten hydration of the skin and diminish transepidermal loss of water (TEWL). Formulations containing 2%, 4%, and 6% of KH (based on OB weight) were prepared. Hydration, TEWL and skin pH were measured; intervals of measurements were as follows: 1, 2, 3, 4, 24 and 48 h. Testing was carried out on 10 men. In terms of hydration, supplementing the OB with 2% KH is optimal, as an 11-19% increase occurs in hydration of stratum corneum (SC). All the formulations with added KH as tested caused TEWL to decline after application. Keratin hydrolysate makes for an excellent occlusive; adding it to OB results in a 30-50% reduction in TEWL after application. KH functions as a humectant as well, as it helps to bind water from the lower layers of the epidermis to the SC. Formulations with additions of 2-6% of KH were stable in structure and did not cause phase separation even after 6 months storage. © 2018 by the authors.

Czech name

—

Czech description

—

Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

—

OECD FORD branch

30216 - Dermatology and venereal diseases

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cosmetics

ISSN

2079-9284

e-ISSN

—

Volume of the periodical

5

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

11

Pages from-to

—

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-85058654819