Effect of polyethylene glycol plasticizer on long-term antibacterial activity and the release profile of bacteriocin nisin from polylactide blends

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F18%3A63521429" target="_blank" >RIV/70883521:28110/18:63521429 - isvavai.cz</a>

Alternative codes found

RIV/70883521:28610/18:63521429

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/pat.4336" target="_blank" >https://onlinelibrary.wiley.com/doi/abs/10.1002/pat.4336</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/pat.4336" target="_blank" >10.1002/pat.4336</a>

Result language

angličtina

Original language name

Effect of polyethylene glycol plasticizer on long-term antibacterial activity and the release profile of bacteriocin nisin from polylactide blends

Original language description

This work describes the synergetic effect of polyethylene glycol (PEG) in polylactide (PLA) blends, wherein the polyether acts as both the plasticizer and functional additive, ensuring the long-term antimicrobial activity of bacteriocin nisin. Two types of PEG with the molecular weights of 1000 and 6000 g.mol−1 (20 wt.%) were used to plasticize the PLA blends. The aforementioned bacteriocin nisin, at concentrations ranging between 0.02 and 0.15 wt.% (8000-60 000 IU.g−1), was incorporated into the samples by the solvent cast technique. The effect of various PEG on the structural, mechanical, and thermal properties of the PLA-based blends were investigated by scanning electron microscopy, Fourier transform infrared spectroscopy, stress-strain analysis, differential scanning calorimetry, and dynamic mechanical analysis, respectively. The antibacterial activity of the samples was detected by the agar diffusion technique against Micrococcus luteus. Furthermore, the antibacterial properties of the samples were tested according the ISO 22196 standard against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus, Listeria monocytogenes) bacterial strains. The nisin was detected by high performance liquid chromatography, the device having been equipped with a UV/vis detector. The results show that the PEG, besides its plasticizing effect, significantly enhances the release profile and sustains long-term antibacterial activity of nisin in a PLA matrix.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10404 - Polymer science

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Polymers for Advanced Technologies

ISSN

1042-7147

e-ISSN

—

Volume of the periodical

29

Issue of the periodical within the volume

8

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

2253-2263

UT code for WoS article

000437840000011

EID of the result in the Scopus database

2-s2.0-85047480426