Immobilization of bacteriocin nisin into a poly(vinyl alcohol) polymer matrix crosslinked with nontoxic dicarboxylic acid

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F16%3A43874542" target="_blank" >RIV/70883521:28610/16:43874542 - isvavai.cz</a>
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1002/app.43674/full" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/app.43674/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/app.43674" target="_blank" >10.1002/app.43674</a>

Result language
angličtina
Original language name
Immobilization of bacteriocin nisin into a poly(vinyl alcohol) polymer matrix crosslinked with nontoxic dicarboxylic acid
Original language description
This work is focused on novel methodology of poly(vinyl alcohol) crosslinking by non-toxic dicarboxylic acid, glutaric acid. The cross-linked system was used as a matrix for immobilization of bacteriocin nisin. Effect of the crosslinking degree on physico-chemical, morphology, mechanical, and thermal properties of poly(vinyl alcohol) films were investigated by using swelling test, Fourier transform infrared spectroscopy, scanning electron microscopy, stress-strain analysis, differential scanning calorimetry, and thermogravimetry. Release profile of the nisin from the cross-linked poly(vinyl alcohol) was studied by high performance liquid chromatography. Antibacterial activity of the prepared systems was tested by agar diffusion test and dilution and spread plate technique. Results showed suitability of glutaric acid as effective crosslinking agent of poly(vinyl alcohol) that acts synergistically with bacteriocin nisin against the tested Gram-positive and Gram-negative bacterial strains.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2016
Confidentiality
C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

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