Core–shell PLA–PVA porous microparticles as carriers for bacteriocin nisin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F17%3A63516637" target="_blank" >RIV/70883521:28610/17:63516637 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1080/02652048.2017.1324919" target="_blank" >http://dx.doi.org/10.1080/02652048.2017.1324919</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/02652048.2017.1324919" target="_blank" >10.1080/02652048.2017.1324919</a>

Result language

angličtina

Original language name

Core–shell PLA–PVA porous microparticles as carriers for bacteriocin nisin

Original language description

This work is focused on preparation of novel porous type of core–shell-structured microparticles based on polylactide (shell) and poly(vinyl alcohol) cross-linked with glutaric acid (GA) (core) prepared by water-in-oil-in-water solvent evaporation technique. The microparticle systems were used as delivery systems for immobilisation of model antibacterial agent–nisin. The effect of cross-linking and the initial amount of nisin on their morphology was investigated using scanning electron microscopy, BET analysis, zeta potential measurement and Fourier transform infra-red spectroscopy. Encapsulation efficiency and release profile of nisin from the microparticles were studied by high performance liquid chromatography. Antibacterial activity of the prepared systems was tested by dilution and spread plate technique. Results showed the microparticles in the size range of 9–16 μm in diameter with spherical multi-hollow core–shell structure. The presence of cross-linking agent GA influences the release profile of the peptide and has synergistic effect on Listeria monocytogenes growth reduction.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10404 - Polymer science

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Microencapsulation

ISSN

0265-2048

e-ISSN

—

Volume of the periodical

34

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

243-249

UT code for WoS article

000405503100002

EID of the result in the Scopus database

2-s2.0-85021127119