Nisin immobilization into polyester based microspheres
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F16%3A43874560" target="_blank" >RIV/70883521:28610/16:43874560 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/16:43874603
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Nisin immobilization into polyester based microspheres
Original language description
This work is focused on preparation of nisin containing multicomponent microspheres comprising a core based on unmodified polyvinyl alcohol (PVA) crosslinked with glutaric acid (GA) at various degrees. The shell of the microspheres consists of biodegradable polylactic acid (PLA). Encapsulation of nisin in PLA/PVA microspheres was conducted by emulsification solvent evaporation technique. Morphology of the microspheres was studied by using electron microscopy. The efficiency of encapsulation and release kinetics of nisin were evaluated by HPLC. The results revealed that the presence of nisin in the microspheres has no significant effect on their morphology. On the contrary, it was found that the crosslinking degree of PVA increases the average size of the prepared microspheres and also broadens their size distribution. Encapsulation efficiency showed higher values for the non-crosslinked (> 90%) that for the crosslinked PVA systems (> 50%).
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
JI - Composite materials
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů