Polypyrrole-derived low molecular weight substances induce neurogenesis in emryonic stem cells

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F22%3A63560381" target="_blank" >RIV/70883521:28110/22:63560381 - isvavai.cz</a>

Alternative codes found

RIV/70883521:28610/22:63560381

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Polypyrrole-derived low molecular weight substances induce neurogenesis in emryonic stem cells

Original language description

Conductive polymers (CP) are used as biomaterials in tissue engineering due to their conductivity, biocompatibility, relatively easy of synthesis and their low cost. An advantageous aspect of CP is the combination of electronic and ionic conductivity. The ability to convert electrical signals to ionic (and vice versa) plays a crucial role in creating an active biointerface. The effect of CP conductivity is interesting in connection with the stimulation of electrosensitive tissues such as nervous or cardiac. Polypyrrole (PPy) is one of the most discussed representatives of CP in tissue engineering. There are many studies where PPy in combination with electric current affects the behavior of cells. However, the PPy precursor, heterocycle pyrrole, also has very interesting properties, as the pyrrole molecule is present in many therapeutic agents. Pyrrole derivatives serve as phannacologically active substances and clearly influencing cellular behavior.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů