Preparation and characterization of gelatin-based porous systems using X-ray tomography

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F23%3A63571141" target="_blank" >RIV/70883521:28110/23:63571141 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/23:63571141
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Preparation and characterization of gelatin-based porous systems using X-ray tomography
Original language description
3D printing of biocompatible materials based on gelatin is one of the possible ways to successfully create structures capable of supporting cells and ensuring their proliferation. The mechanical properties of pure gelatin are not suitable for additive manufacturing and it is necessary to improve them, for example, by cross-linking, where the Schiff base method was chosen as the most suitable. In the experiments, gelatin (rabbit and bovine) was mixed with oxidized dextran in different ratios (1 to 1, 1 to 2, 1 to 3) with the addition of activating agents (NH3 and TEA). The resulting material was then printed on a 3D bioprinter BIO X (Cellink) in layers (1, 3, 5) with a predefined pattern. These scaffolds were subsequently subjected to porosity analysis in both the native and lyophilized states using scanning electron microscopy and computed tomography. The results confirm the theory that the prepared material could serve as a support material for printing cells in tissue engineering in the future.
Czech name
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Czech description
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Project
<a href="/en/project/GA22-33307S" target="_blank" >GA22-33307S: Development of novel 3D hierarchically structured polysaccharides and proteins porous systems</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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