Nonlinear oscillatory shear tests of pressure-sensitive adhesives (PSAs) designed for transdermal therapeutic systems (TTS)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F21%3A63539103" target="_blank" >RIV/70883521:28610/21:63539103 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28110/21:63539103
Result on the web
<a href="https://link.springer.com/article/10.1007/s00397-021-01280-6" target="_blank" >https://link.springer.com/article/10.1007/s00397-021-01280-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00397-021-01280-6" target="_blank" >10.1007/s00397-021-01280-6</a>
Alternative languages
Result language
angličtina
Original language name
Nonlinear oscillatory shear tests of pressure-sensitive adhesives (PSAs) designed for transdermal therapeutic systems (TTS)
Original language description
Transdermal therapeutic systems (TTS) based on pressure-sensitive adhesives (PSAs) allow for the application of pharmaceutical substances via diffusion through the skin. The rheological performance of PSA is largely investigated within small amplitude oscillatory shear (typically up to 1 %), although the skin motions exceed strains beyond 40 %. In this paper, amine-compatible (AC) and non-amine-compatible (NAC) silicone-based PSA compounds differing in the resin content were subjected to strain amplitude sweeps in a twin drive rheometer. Carreau-Yasuda-like fitting of storage and loss moduli curves intercepts the substantial effect of resin content on both compounds; up to four times higher, moduli of AC compounds were determined in SAOS, and their higher molecular mass combined with enhanced interactions contributed to an earlier transition to the nonlinear viscoelastic region. In the nonlinear range, elastic and viscous properties are affected by strains in a different manner with the trend favorable for the PSA application as TTS. The third relative higher harmonic from Fourier transformation I-3/1 as well as intra-cycle strain stiffening and shear thickening ratios provide information relevant for an optimization of PSA subjected to large deformations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20301 - Mechanical engineering
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Rheologica Acta
ISSN
0035-4511
e-ISSN
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Volume of the periodical
60
Issue of the periodical within the volume
Neuveden
Country of publishing house
US - UNITED STATES
Number of pages
18
Pages from-to
"553–570"
UT code for WoS article
000675036000002
EID of the result in the Scopus database
2-s2.0-85110872944