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Nonlinear oscillatory shear tests of pressure-sensitive adhesives (PSAs) designed for transdermal therapeutic systems (TTS)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F21%3A63539103" target="_blank" >RIV/70883521:28610/21:63539103 - isvavai.cz</a>

  • Alternative codes found

    RIV/70883521:28110/21:63539103

  • Result on the web

    <a href="https://link.springer.com/article/10.1007/s00397-021-01280-6" target="_blank" >https://link.springer.com/article/10.1007/s00397-021-01280-6</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00397-021-01280-6" target="_blank" >10.1007/s00397-021-01280-6</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Nonlinear oscillatory shear tests of pressure-sensitive adhesives (PSAs) designed for transdermal therapeutic systems (TTS)

  • Original language description

    Transdermal therapeutic systems (TTS) based on pressure-sensitive adhesives (PSAs) allow for the application of pharmaceutical substances via diffusion through the skin. The rheological performance of PSA is largely investigated within small amplitude oscillatory shear (typically up to 1 %), although the skin motions exceed strains beyond 40 %. In this paper, amine-compatible (AC) and non-amine-compatible (NAC) silicone-based PSA compounds differing in the resin content were subjected to strain amplitude sweeps in a twin drive rheometer. Carreau-Yasuda-like fitting of storage and loss moduli curves intercepts the substantial effect of resin content on both compounds; up to four times higher, moduli of AC compounds were determined in SAOS, and their higher molecular mass combined with enhanced interactions contributed to an earlier transition to the nonlinear viscoelastic region. In the nonlinear range, elastic and viscous properties are affected by strains in a different manner with the trend favorable for the PSA application as TTS. The third relative higher harmonic from Fourier transformation I-3/1 as well as intra-cycle strain stiffening and shear thickening ratios provide information relevant for an optimization of PSA subjected to large deformations.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20301 - Mechanical engineering

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Rheologica Acta

  • ISSN

    0035-4511

  • e-ISSN

  • Volume of the periodical

    60

  • Issue of the periodical within the volume

    Neuveden

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    18

  • Pages from-to

    "553–570"

  • UT code for WoS article

    000675036000002

  • EID of the result in the Scopus database

    2-s2.0-85110872944