Host-guest paracetamol/cyclodextrin complex formation evaluated from coupled diffusion measurements
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F21%3A63539138" target="_blank" >RIV/70883521:28610/21:63539138 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28110/21:63539138
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0021961421001658?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0021961421001658?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jct.2021.106551" target="_blank" >10.1016/j.jct.2021.106551</a>
Alternative languages
Result language
angličtina
Original language name
Host-guest paracetamol/cyclodextrin complex formation evaluated from coupled diffusion measurements
Original language description
Ternary mutual diffusion coefficients (D11, D22, D12 and D21) measured by the Taylor dispersion method are reported for aqueous solutions of paracetamol (1) in the presence of β-cyclodextrin (β-CD) (2) at 298.15 K and solute concentrations up to 0.050 (mol dm−3). The diffusion of paracetamol and β-CD is coupled, as indicated by non-zero values of the cross-diffusion coefficients, D12 and D21 measuring interactions between the fluxes of the drug and the carbohydrate. The measured ternary diffusion coefficients are in close agreement with the diffusion coefficients predicted by a model assuming a 1:1 (paracetamol):(β-CD) complex. The association constant K = 27 (mol−1 dm3) for the formation of the complex was estimated from the diffusion data.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Chemical Thermodynamics
ISSN
0021-9614
e-ISSN
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Volume of the periodical
161
Issue of the periodical within the volume
Neuveden
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
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UT code for WoS article
000687712500016
EID of the result in the Scopus database
2-s2.0-85109451468