Polymer-based electrochemical sensor: Fast, accurate, and simple insulin diagnostics tool
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F23%3A63567738" target="_blank" >RIV/70883521:28610/23:63567738 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007/s12678-023-00827-w" target="_blank" >https://link.springer.com/article/10.1007/s12678-023-00827-w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12678-023-00827-w" target="_blank" >10.1007/s12678-023-00827-w</a>
Alternative languages
Result language
angličtina
Original language name
Polymer-based electrochemical sensor: Fast, accurate, and simple insulin diagnostics tool
Original language description
Study of the use of polymers with higher conductivity like polypyrrole, and polyaniline in the electrochemical insulin sensors can overcome the drawbacks arising from the ongoing use of non-conductive polymer membrane. Conductive polymer membranes maintain the positive properties of polymers, like improved stability, reproducibility, and even increase the current response of the prepared sensor toward insulin oxidation. Three different screen-printed electrodes modified with polyaniline, polypyrrole, or chitosan with electrochemically deposited nickel nanoparticles ensuring insulin oxidation were prepared. The electrode morphology was examined via SEM with EDX analysis. Also, the electroactive surface area and stability were determined by voltammetric methods. Based on the results, the SPCEs modified by polypyrrole and nickel nanoparticles were determined as the most appropriate for the insulin determination. The NiNPs-PPy-SPCE exhibited a linear range (500 nM–5 µM), a low-down limit of detection (38 nM), high sensitivity (3.98 µA/µM), and excellent result from insulin determination in real samples (human blood serum). The results confirmed the high potential of developed sensor for future research focused on detection of insulin via electrochemistry methods in clinical samples.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30404 - Biomaterials (as related to medical implants, devices, sensors)
Result continuities
Project
<a href="/en/project/EF18_053%2F0017879" target="_blank" >EF18_053/0017879: International mobility of UTB researchers in Zlín II</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrocatalysis
ISSN
1868-2529
e-ISSN
1868-5994
Volume of the periodical
14
Issue of the periodical within the volume
Neuveden
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
"697–707"
UT code for WoS article
000985798600001
EID of the result in the Scopus database
2-s2.0-85159042606