Biodegradable zinc-based materials with a polymer coating designed for biomedical applications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F23%3A63569661" target="_blank" >RIV/70883521:28610/23:63569661 - isvavai.cz</a>
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/app.54773" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/app.54773</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/app.54773" target="_blank" >10.1002/app.54773</a>
Alternative languages
Result language
angličtina
Original language name
Biodegradable zinc-based materials with a polymer coating designed for biomedical applications
Original language description
Over the last decades, biodegradable metals have gained popularity for biomedical applications due to their ability to assist in tissue healing. These materials degrade in vivo, while the corrosion products formed are either absorbed or excreted by the body, and no further surgical intervention is required for removal. Intensive research has been carried out mainly on degradable biomaterials based on Mg and Fe. In recent years, zinc-based degradable biomaterials have been explored by the biomedical community for their intrinsic physiological relevance, desirable biocompatibility, intermediate degradation rate, tuneable mechanical properties and pro-regeneration properties. Since pure Zn does not exhibit sufficient mechanical properties for orthopedic applications, various Zn alloys with better properties are being developed. In this work, the combined effect of minor Fe addition to Zn and a polyethyleneglycol (PEG) coating on the surface morphology, degradation, cytotoxicity and mechanical properties of Zn-based materials was studied. There are several studies regarding the influence of the production of Zn alloys, but the effect of polymer coating on the properties of Zn-based materials has not been reported yet. A positive effect of Fe addition and polymer coating on the degradation rate and mechanical properties was observed. However, a reduction in biocompatibility was also detected.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30404 - Biomaterials (as related to medical implants, devices, sensors)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Applied Polymer Science
ISSN
0021-8995
e-ISSN
1097-4628
Volume of the periodical
Neuveden
Issue of the periodical within the volume
Neuveden
Country of publishing house
US - UNITED STATES
Number of pages
23
Pages from-to
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UT code for WoS article
001083787800001
EID of the result in the Scopus database
2-s2.0-85173721379