Silver/Chitosan Antimicrobial Nanocomposites Coating for Medical Devices: Comparison of Nanofiller Effect Prepared via Chemical Reduction and Biosynthesis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F71009396%3A_____%2F19%3AN0000020" target="_blank" >RIV/71009396:_____/19:N0000020 - isvavai.cz</a>
Result on the web
<a href="https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000005/art00065" target="_blank" >https://www.ingentaconnect.com/content/asp/jnn/2019/00000019/00000005/art00065</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1166/jnn.2019.15863" target="_blank" >10.1166/jnn.2019.15863</a>
Alternative languages
Result language
angličtina
Original language name
Silver/Chitosan Antimicrobial Nanocomposites Coating for Medical Devices: Comparison of Nanofiller Effect Prepared via Chemical Reduction and Biosynthesis
Original language description
Medical devices have an essential part in healthcare system in recent years, such as usage of heart valves, several types of stents and implants devices in patients. However, bacterial infection of medical devices causes critical issues for patients due to attachment of bacteria and formation of biofilm onto the medical devices. Therefore, finding an effective antibacterial coating to prevent biofilm formation and infection is our goal. In this study, we developed silver/chitosan nanocomposites for antimicrobial coating system by chemical and green methods using sodium borohydride and linden extract, respectively. Silver is known as a strong inorganic antimicrobial agent to kill bacteria by inactivating enzymes and dysfunction bacterial cell membranes. By immobilizing silver nanoparticles on chitosan biopolymer can prevent agglomeration of nanoparticles, besides it can improve the biocompatibility. We characterized properties of our silver chitosan nanocomposites samples using particle size distribution, ultraviolet-visible spectroscopy, X-ray diffraction analysis and scanning electron microscopy. Effective antimicrobial film preventing biofilm formation on medical devices was designed. Antimicrobial testing confirmed antimicrobial properties however variable for each type of nanosilver.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
ISSN
1533-4880
e-ISSN
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Volume of the periodical
19
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
2938-2942
UT code for WoS article
000458402700065
EID of the result in the Scopus database
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