Cooling of the auditory cortex modifies neuronal activity in the inferior colliculus in rats

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F71226401%3A_____%2F15%3A%231006872" target="_blank" >RIV/71226401:_____/15:#1006872 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/16:00458702 RIV/00216208:11120/16:43910460 RIV/71226401:_____/16:N0000195
Result on the web
<a href="http://dx.doi.org/10.1016/j.heares.2015.10.021" target="_blank" >http://dx.doi.org/10.1016/j.heares.2015.10.021</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.heares.2015.10.021" target="_blank" >10.1016/j.heares.2015.10.021</a>

Result language
angličtina
Original language name
Cooling of the auditory cortex modifies neuronal activity in the inferior colliculus in rats
Original language description
There are powerful pathways descending from the auditory cortex (AC) to the inferior colliculus (IC), yet their function is not fully understood. The aim of this study is to examine the effects of a reversible cortical inactivation, achieved by cooling of the AC, on the responses of neurons in the rat IC. Extracellular single-unit or multi-unit activity was recorded in the IC of anaesthetized rats with a 16-channel multielectrode probe introduced along the IC dorso-ventral axis through the dorsal cortex(DCIC) to the central nucleus of the IC (CIC). Cooling of the AC produced an increase in spontaneous activity and magnitude of the sound-evoked response in 47% of the IC neurons. Maximal changes in the neuronal activity were observed in the DCIC and thecentral part of the CIC. The final segments of the sustained responses to 60 ms stimuli and the off responses were more affected than the onset segments. Inactivation of the AC resulted in a suppression of the post-excitatory inhibition
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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