Ochratoxin A: Developmental and reproductive toxicity - an overview
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F13%3A00010261" target="_blank" >RIV/75010330:_____/13:00010261 - isvavai.cz</a>
Alternative codes found
RIV/62690094:18470/13:50001978 RIV/00216208:11160/13:10282178
Result on the web
<a href="http://dx.doi.org/10.1002/bdrb.21091" target="_blank" >http://dx.doi.org/10.1002/bdrb.21091</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/bdrb.21091" target="_blank" >10.1002/bdrb.21091</a>
Alternative languages
Result language
angličtina
Original language name
Ochratoxin A: Developmental and reproductive toxicity - an overview
Original language description
Ochratoxin A (OTA) is nephrotoxic, hepatotoxic, reprotoxic, embryotoxic, teratogenic, neurotoxic, immunotoxic, and carcinogenic for laboratory and farm animals. Male and female reproductive health has deteriorated in many countries during the last few decades. A number of toxins in environment are suspected to affect reproductive system in male and female. OTA is one of them. OTA has been found to be teratogenic in several animal models including rat, mouse, hamster, quail, and chick, with reduced birthweight and craniofacial abnormalities being the most common signs. The presence of OTA also results in congenital defects in the fetus. Neither the potential of OTA to cause malformations in human nor its teratogenic mode of action is known. Exposure toOTA leads to increased embryo lethality manifested as resorptions or dead fetuses. The mechanism of OTA transfer across human placenta (e.g., which transporters are involved in the transfer mechanism) is not fully understood. Some of the
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT12051" target="_blank" >NT12051: Ochratoxin A ? health risk assessment for selected population groups in the Czech Republic</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Birth Defects Research Part B: Developmental and Reproductive Toxicology
ISSN
1542-9733
e-ISSN
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Volume of the periodical
98
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
493-502
UT code for WoS article
000331142300005
EID of the result in the Scopus database
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