Identification of 50 class D beta-lactamases and 65 Acinetobacter-derived cephalosporinases in Acinetobacter spp.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F14%3A00010668" target="_blank" >RIV/75010330:_____/14:00010668 - isvavai.cz</a>
Result on the web
<a href="http://aac.asm.org/content/58/2/936" target="_blank" >http://aac.asm.org/content/58/2/936</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1128/AAC.01261-13" target="_blank" >10.1128/AAC.01261-13</a>
Alternative languages
Result language
angličtina
Original language name
Identification of 50 class D beta-lactamases and 65 Acinetobacter-derived cephalosporinases in Acinetobacter spp.
Original language description
Whole-genome sequencing of a collection of 103 Acinetobacter strains belonging to 22 validly named species and another 16 putative species allowed detection of genes for 50 new class D beta-lactamases and 65 new Acinetobacter-derived cephalosporinases (ADC). All oxacillinases (OXA) contained the three typical motifs of class D beta-lactamases, STFK, (F/Y) GN, and K(S/T) G. The phylogenetic tree drawn from the OXA sequences led to an increase in the number of OXA groups from 7 to 18. The topologies of the OXA and RpoB phylogenetic trees were similar, supporting the ancient acquisition of bla(OXA) genes by Acinetobacter species. The class D beta-lactamase genes appeared to be intrinsic to several species, such as Acinetobacter baumannii, Acinetobacter pittii, Acinetobacter calcoaceticus, and Acinetobacter lwoffii. Neither bla(OXA-40/143)-nor bla(OXA-58)-like genes were detected, and their origin remains therefore unknown. The phylogenetic tree analysis based on the alignment of the seque
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA13-26693S" target="_blank" >GA13-26693S: Genetic diversity and phylogeny of the genus Acinetobacter in natural ecosystems.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Antimicrobial Agents and Chemotherapy
ISSN
0066-4804
e-ISSN
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Volume of the periodical
58
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
936-949
UT code for WoS article
000330637500039
EID of the result in the Scopus database
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