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Cell uptake of titanium dioxide nanoparticle

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F15%3A00011147" target="_blank" >RIV/75010330:_____/15:00011147 - isvavai.cz</a>

  • Result on the web

    <a href="http://iicbe.org/upload/9493C0615081.pdf" target="_blank" >http://iicbe.org/upload/9493C0615081.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cell uptake of titanium dioxide nanoparticle

  • Original language description

    Titanium dioxide (TiO2) represents one of the most frequently applied nanomaterials but mechanisms through which TiO2 nanoparticles induce cell death are mostly unclear. The aim of this work was to evaluate cell uptake of TiO2 nanoparticles (NPs) by atomic force microscopy and confocal Raman microscopy on BJ (human fibroblasts from foreskin) cell lines. We have found that NPs aggregate in certain intracellular regions. The aggregates were formed after penetration of NPs into cytoplasm through their endosomal transport. The cell viability changes in a concentration dependent manner were determined by methylthiazol tetrazolium bromide (MTT) viability assay.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FM - Hygiene

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT14060" target="_blank" >NT14060: Nanotechnologies and consumer health risks</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    IICBE Int'l Conference Proceedings on International Conference on chemical, civil and Environmental Engineering (CCEE-2015), International Conference on Medical Genetics, Cellular and Molecular Biology, Pharmaceutical and Food Sciences (GCMBPF-2015), International Conference of Social Science, Medicine and Nursing (SSMN-2015)

  • ISBN

    978-93-84422-23-3

  • ISSN

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

    140-142

  • Publisher name

    IICBEE

  • Place of publication

  • Event location

    Istanbul

  • Event date

    Jun 5, 2015

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article