Cell uptake of titanium dioxide nanoparticle

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F15%3A00011147" target="_blank" >RIV/75010330:_____/15:00011147 - isvavai.cz</a>
Result on the web
<a href="http://iicbe.org/upload/9493C0615081.pdf" target="_blank" >http://iicbe.org/upload/9493C0615081.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Cell uptake of titanium dioxide nanoparticle
Original language description
Titanium dioxide (TiO2) represents one of the most frequently applied nanomaterials but mechanisms through which TiO2 nanoparticles induce cell death are mostly unclear. The aim of this work was to evaluate cell uptake of TiO2 nanoparticles (NPs) by atomic force microscopy and confocal Raman microscopy on BJ (human fibroblasts from foreskin) cell lines. We have found that NPs aggregate in certain intracellular regions. The aggregates were formed after penetration of NPs into cytoplasm through their endosomal transport. The cell viability changes in a concentration dependent manner were determined by methylthiazol tetrazolium bromide (MTT) viability assay.
Czech name
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Czech description
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Project
<a href="/en/project/NT14060" target="_blank" >NT14060: Nanotechnologies and consumer health risks</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
IICBE Int'l Conference Proceedings on International Conference on chemical, civil and Environmental Engineering (CCEE-2015), International Conference on Medical Genetics, Cellular and Molecular Biology, Pharmaceutical and Food Sciences (GCMBPF-2015), International Conference of Social Science, Medicine and Nursing (SSMN-2015)
ISBN
978-93-84422-23-3
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
140-142
Publisher name
IICBEE
Place of publication
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Event location
Istanbul
Event date
Jun 5, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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