Protective effect of vaccination against mumps complications, Czech Republic, 2007-2012

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F75010330%3A_____%2F16%3A00011283" target="_blank" >RIV/75010330:_____/16:00011283 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/16:43911203

Result on the web

<a href="http://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-016-2958-4" target="_blank" >http://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-016-2958-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12889-016-2958-4" target="_blank" >10.1186/s12889-016-2958-4</a>

Result language

angličtina

Original language name

Protective effect of vaccination against mumps complications, Czech Republic, 2007-2012

Original language description

In the Czech Republic, two-dose immunization against mumps achieves 98 % coverage. The routine reporting detects mumps cases, clinical complications, and hospital admissions in unvaccinated but also in vaccinated individuals. Using surveillance data of patients with mumps we assessed the effectiveness of mumps vaccination on mumps clinical complications and hospitalization need. We also investigated the effect of the time since immunization. We analysed data on incident mumps cases reported to the Czech national surveillance system in 2007-2012. Results: From total of 9663 mumps analysed cases 5600 (58 %) occurred in males. The mean age at the disease onset was 17.3, median 16 years. Ninety percent of the study patients had no complications, while 1.6 % developed meningitis, 0.2 % encephalitis, and 0.6 % pancreatitis. Mumps orchitis occurred in 659 (11.8 %) male cases. In total, 1192 (12.3 %) patients required hospitalization. Two doses of vaccine received by 81.8 % cases significantly reduced the risk of hospitalization. This study demonstrates a significant preventive effect of two-dose vaccination against mumps complications (orchitis, meningitis, or encephalitis) and hospitalization for mumps. The risk of complications increases with time interval from vaccination. Teenagers and young adults were the most affected age groups.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

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Project

<a href="/en/project/NT14059" target="_blank" >NT14059: Clinically manifest mumps in the vaccinated population – genotyping of the causative virus and patient’s serological profile.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BMC Public Health

ISSN

1471-2458

e-ISSN

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Volume of the periodical

16

Issue of the periodical within the volume

April

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

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UT code for WoS article

000373257600002

EID of the result in the Scopus database

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